Tag: clinical trials

Pulse oximeters

COVID-19 puts the spotlight on an unexpected racial disparity in health care

Evidence increasingly suggests that pulse oximeters, the little finger clips that measure blood oxygen, overestimate the blood oxygenation in Black patients. It's a problem that's been discussed a long time that took a pandemic to bring to public consciousness. How can SBM decrease or eliminate such healthcare disparities?

/ July 18, 2022

Gender-Affirming Care is Not Experimental, Part II

A lot of the "facts" about providing healthcare to transgender youth turn out to be not actually facts. We present here a summary of the evidence relating to transition-related health care for transgender adolescents.

Homeopathy and Pre-Registered Trials

Preregistering clinical trials is a great idea, but we have to actually track registration.

/ May 18, 2022
Signos Glucose Monitor

Signos Sells a Continuous Glucose Monitor, But Not to Diabetics

Signos is asking customers to pay for the privilege of testing their glucose monitoring system.

/ May 17, 2022
The Good, The Bad, and The Ugly

How to design high quality acupuncture trials: The Good, The Bad, and The Ugly

Acupuncture advocates have published guidelines for "rigorous" acupuncture randomized controlled trials. While that sounds good on the surface, the devil is in the details, which reveal that the dedication to scientific rigor is perhaps not so strong.

/ April 11, 2022
The BMJ's Facebook logo

What the heck happened to The BMJ?

Last week, The BMJ published an "exposé" by Paul Thacker alleging patient unblinding, data falsification, and other wrongdoing by a company running three sites for the massive clinical trial of the Pfizer COVID-19 vaccine. It was a highly biased story embraced by antivaxxers, with a deceptively framed narrative and claims not placed into proper context, leading me to look into the broader...

/ November 8, 2021
Pfizer/BioNTech COVID-19 vaccine

To unblind or not to unblind? That is the question about clinical trials of COVID-19 vaccines

Antivaccine alternative health tycoon Joe Mercola claims that the unblinding of participants in the clinical trials of Moderna and Pfizer COVID-19 vaccines was intended to "blow up the trials" and undermine the science, making it impossible ever to identify long term adverse events. What he's really doing is deceptively oversimplifying complex ethical and scientific issues surrounding these trials in the middle of...

/ April 26, 2021
Stem cells

Dubious stem cell trials for autism and the darker side of quackademic medicine

Despite a lack of evidence, Duke University is all-in on stem cells for autism, thanks to a billionaire benefactor and a highly dodgy for-profit Panama stem cell clinic. How did this come to be and what will be the outcome? Whatever the answers to these questions, it is clear that arrangements like the one between Duke University and The Stem Cell Institute...

/ November 2, 2020

HCQTrial.com: Astroturf and disinformation about hydroxychloroquine and COVID-19 on steroids

Late last week, a "study" published on HCQTrial.com by an anonymous source claiming to be a group of PhD scientists went viral. It claimed that countries that used hydroxychloroquine to treat COVID-19 had a 79% lower fatality rate than those who didn't. It was horrible science and quickly debunked on Twitter by several epidemiologists. That didn't stop it from going viral. Disinformation...

/ August 10, 2020